FIELD TRIALS OF JAPANESE ENCEPHALITIS VIRUS VACCINES IN NON-ENDEMIC AREA
نویسندگان
چکیده
منابع مشابه
Japanese Encephalitis Vaccines.
Japanese encephalitis (JE) is a significant human health concern in Asia, Indonesia and parts of Australia with more than 3 billion people potentially at risk of infection with Japanese encephalitis virus (JEV), the causative agent of JE. Given the risk to human health and the theoretical potential for JEV use as a bioweapon, the development of safe and effective vaccines to prevent JEV infecti...
متن کاملJapanese encephalitis and vaccines
Japanese encephalitis (JE) is an inflammatory disease in the central nervous system including cerebrum, cerebellum, and spinal cord caused by viral infection transmitted by Culex mosquitoes. JE is an important disease in East, Southeast, and South Asia, which lead to serious complication and high mortality rate. Complete cure is shown in only one third of the patients. However the ratio of symp...
متن کاملCurrent Scenario of Vaccines for Japanese Encephalitis
Currently various countries in South-East Asia, including India, are facing disaster due to Acute Encephalitis Syndrome (AES), which is primarily caused by Japanese Encephalitis Virus (JEV). A dirty environment and a lack of awareness about the risks associated with mosquito bites may be one of the reasons of the outbreak. Japanese encephalitis is a lethal neuroviral infection for which there i...
متن کاملEntomological and serological investigation of Japanese encephalitis in endemic area of eastern Uttar Pradesh, India.
BACKGROUND & OBJECTIVES Japanese encephalitis virus (JEV), a mosquito borne pathogen, is one of the major causes of viral encephalitis in eastern Uttar Pradesh, India. The objective of this work was to evaluate the entomological based virological surveillance of Japanese encephalitis (JE) in the highly endemic area of eastern Uttar Pradesh. METHODS The study was carried out during September 2...
متن کاملNeuropathogenesis of Japanese encephalitis virus.
In the central nervous system, the Japanese encephalitis virus can replicate only in neurons. The mechanism of the type of neurotropism was analyzed. The susceptibility to Japanese encephalitis virus infection in the rat brain was closely associated with neuronal immaturity. The initial specific binding of the virus to cells is one of the reasons for neurotropism of the Japanese encephalitis vi...
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ژورنال
عنوان ژورنال: Uirusu
سال: 1968
ISSN: 0042-6857,1884-3433
DOI: 10.2222/jsv.18.305